AWARds – A gOOd REAd – AppOINTMENTs
A good read –
Publications from the EMBO Community
Events
EMBO MEMBERS
EMBO Member George Thomas is one of the organizers of the IDIBELL Cancer Conference on Personalized Cancer Medicine that is to take place in Barcelona from 3 – 4 December 2012. Special focus will be on epigenetics and DNA repair and metabolism and cell signal- ling with the latest clinical applications.
More at: http://bocemtium.com/icc2012/index.php/icc/2012/index.html.var Awards of excellence
CLIP-seq of eIF4AIII reveals transcriptome-wide mapping of the human exon junction complex
Zhen Wang (EMBO Fellow) et al.
Nature Structural & Molecular Biology | 21 October 2012 doi: 10.1038/nsmb.2420
A bimodular mechanism of calcium control in eukaryotes
Henning Tidow (EMBO Fellow), Poul Nissen (EMBO Member) et al. Nature | 21 October 2012
doi: 10.1038/nature11539
DAxx envelops an H3.3–H4 dimer for H3.3-specific recognition
Simon J. Elsässer (EMBO Fellow) et al. Nature | 17 October 2012
doi: 10.1038/nature11608
The IL-22 – IL-22BP axis is regulated by the inflammasome and modulates tumorigenesis in the intestine
Nicola Gagliani (EMBO Fellow) et al. Nature | 17 October 2012
doi: 10.1038/nature11535
Epistasis as the primary factor in molecular evolution
Fyodor A. Kondrashov
(EMBO Young Investigator) et al. Nature | 14 October 2012 doi:10.1038/nature11510
The p110d isoform of the kinase PI(3) K controls the subcellular compartmen- talization of TLR4 signaling and protects from endotoxic shock
Ezra Aksoy (EMBO Fellow) ,
Bart Vanhaesebroeck (EMBO Member) et al.
Nature Immunology | 30 September 2012 doi:10.1038/ni.2426
Positive modulation of a Cys-loop acetylcholine receptor by an auxiliary transmembrane subunit
Thomas Boulin, Christian Stigloher (EMBO Fellows) et al.
Nature Neuroscience | 26 August 2012 doi:10.1038/nn.3197
A PML – PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
Arkaitz Carracedo (EMBO Fellow),
Pier Paolo Pandolfi (EMBO Member) et al.
Nature Medicine | 19 August 2012 doi:10.1038/nm.2882
Distinct contribution of stem and progen- itor cells to epidermal maintenance
Cédric Blanpain
(EMBO Young Investigator) et al. Nature | 2 September 2012 doi:10.1038/nature11393
Structural basis for RNA duplex recognition and unwinding by the DEAD-box helicase Mss116p
Anna L. Mallam (EMBO Fellow) et al. Nature | 2 September 2012 doi:10.1038/nature11402
Dopamine neurons modulate pheromone responses in Drosophila courtship learning
Eleftetheria Vrontou (EMBO Fellow), Barry J. Dickson (EMBO Member) et al. Nature | 19 August 2012 doi:10.1038/nature11345
Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium
Amélie Montel-Hagen (EMBO Fellow) et al. Cell | 3 August 2012
doi: 10.1016/j.cell.2012.06.026
BLD10/CEP135 is a microtubule- associated protein that controls the formation of the flagellum central microtubule pair
Monica Bettencourt-Dias (EMBO Young Investigator) et al. Developmental Cell | August 2012
doi: 10.1016/j.devcel.2012.06.001
Defining the mode of tumour growth by clonal analysis
Cédric Blanpain
(EMBO Young Investigator) et al.
Nature | 1 August 2012 doi: 10.1038/nature11344
The toxin–antitoxin proteins RelBE2Spn of Streptococcus pneumoniae: Characterization and association to their DNA target
Manuel Espinosa (EMBO Member) et al. PROTEINS:
Structure, Function, and Bioinformatics | July 2012 doi: 10.1002/prot.24081
Chromatin organization is a major influ- ence on regional mutation rates in human cancer cells
Ben Lehner (EMBO Young Investigator) et al. Nature | 22 July 2012
doi: 10.1038/nature11273
Viral immune modulators perturb the human molecular network by common and unique strategies
Andreas Pichlmair (EMBO Fellow),
Giulio Superti-Furga (EMBO Member) et al.
Nature | 18 July 2012
doi: 10.1038/nature11289
Tandem fluorescent protein timers for in vivo analysis of protein dynamics
Anton Khmelinskii (EMBO Fellow) et al.
Nature Biotechnology | 24 June 2012 doi: 10.1038/nbt.2281
EMBO MEMBERS
Körber European Science Prize
Körber Foundation
Matthias Mann, a physicist and bioinfor- matician at the Max-Planck-Institute of Biochemistry in Martinsried, Germany, won the 2012 Körber European Science Prize for his ground-breaking work on the proteome, the entire complement of proteins in a living organism. The prize comes with an award of 750,000 euros. The proteomics pioneer also received the 2012 Ernst Schering Prize worth 50,000 euros and awarded by the Schering Foundation Berlin.
US National Academy of Sciences
George Coupland from the Max-Planck- Institute for Plant Breeding Research in Cologne, Germany, was elected a foreign associate of the US National Academy of Sciences this year.
Millennium Technology Prize
Technology Academy Finland
EMBO Member Shinya Yamanaka and Linus Torvalds are joint Grand Winners of the 2012 Millennium Technology Prize, one of the world’s major technology prizes. The Japanese scientist received it in recognition of his discovery of a new method to develop induced pluripotent stem cells for medical research. The prize worth 1,2 million euros was split between the two researchers and presented by the president of the Republic of Finland last June.
EMBO YOUNG INVESTIGATORS
ASCB Women in Cell Biology award
American Society of Cell Biology
Sophie Martin from the University of Lausanne, Switzerland, is the winner of the 2012 ASCB Women in Cell Biology Junior award. The prize recognizes female scien- tists in an early stage of their careers who make exceptional scientific contributions to cell biology, develop a strong independent research program, and exhibit the potential for continuing a high level of scientific endeavour and leadership. She will receive the award at the ASCB annual meeting in San Francisco, United States, in December 2012.
Appointments
EMBO MEMBER
The Gulbenkian Science Institute in Oeiras, Portugal, announced the appointment
of EMBO Member Jonathan Howard as its new director as of 1 October 2012. He succeeds António Coutinho, who stepped
Balzan Prize
International Balzan Prize Foundation
David Baulcombe of the University of Cambridge, United Kingdom, received
the prize for his work on the epigenetic effects of stress on plant cells and tissue. Baulcombe says the prize of 750,000 Swiss Francs (approximately 620,000 euros) will help start a new line of epigenetic research into algae. The Italy-based International Balzan Prize Foundation annually funds research awards for scholars, scientists, and artists who it considers to have been overlooked by other prestigious awards.
Albert Lasker
Basic Medical Research Award Lasker Foundation
This year’s Lasker Award for basic medical research goes to EMBO Associate Member Ronald Vale and his colleagues Michael Sheetz and James Spudich for discoveries concerning cytoskeletal motor proteins, machines that move cargoes within cells, contract muscles, and enable cell move- ments. The Lasker Awards, which carry an honorarium of 250,000 US dollars for each category, were presented at a ceremony in New York City last September.
ASBMB-Merck Award
American Society for Biochemistry and Molecular Biology / Merck
Vivek Malhotra of the Centre for Genomic Regulation in Barcelona, Spain, received the ASBMB-Merck Award for Studies on the mechanism of secretory cargo sorting and transport carrier biogenesis during conventional and unconventional protein secretion.
EACR Cancer Researcher Award Lecture
European Association for Cancer Research / Pezcoller Foundation
Eric So from King’s College London, United Kingdom, is the winner of this award that recognizes academic excellence in the field of cancer research. He is the first recipient of this award worth 10.000 euros. He gave the Pezcoller Foundation – EACR Award Lecture at the biennial congress of EACR, which this year was held in Barcelona. The primary goal of Eric So’s research is to char- acterize the mechanisms of transcriptional regulation that are corrupted in leukemia.
down after 14 years as the institute’s direc- tor. Howard, a prominent British immu- nologist, is also a professor at the Institute of Genetics of the University of Cologne.
Editorial
Managing Editor Barry Whyte
Editor Yvonne Kaul
proofreading Meryl Schneider
print layout Uta Mackensen
Web version Aditya Kusuma Jati E-newsletter Sandra Krahl, Katja Linssen
©2012 EMBO
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